Teach the New Standard
of Medicine
The Institute is searching for 24 visionary clinicians to author the definitive curriculum on systems biology.
Will you be one of them?
The Founding Fellows
We are not just hiring teachers; we are selecting the architects of the next medical paradigm. Join a cohort of world-class experts and leave your mark on the history of medical education.
Study Modules
- Differential Endocrinology
- Biochemistry & Biology
- Immunology & Chronic Inflammation
- Differential Gastroenterology
- Metabolism & Mitochondria
- Systemic Integration & Advanced Practice
Differential Endocrinology
Hormonal Fundamentals & Thyroid
A course focused on hormone physiology, the hypothalamic–pituitary axis, steroidogenesis, and a functional approach to the thyroid (from hormone synthesis to the interpretation of lab results).
Pregnenolone, Adrenal Axis, Cortisol & DHEA
A course dedicated to the stress–energy axis: pregnenolone, cortisol, DHEA, circadian rhythms, and functional regulation of the adrenal glands.
Female Sex Hormones, Cycles, Contraceptive Pill, Endometriosis & Menopause
A course focused on functional gynecology: estrogens, progesterone, menstrual cycles, oral contraceptives, amenorrhea, endometriosis, perimenopause and menopause.
Androgens, PCOS, Prostate & Prolactin
A course dedicated to androgens (in both men and women), PCOS, androgen-related disorders (BPH, alopecia, androgen deficiency), and prolactin.
Biochemistry & Biology
Macromolecules & Clinical Nutrients
A course focused on proteins, carbohydrates, lipids, vitamins and minerals, considered as concrete biochemical levers to understand lab results and patient metabolic profiles.
Enzymes, Cofactors & Key Metabolic Pathways
A course dedicated to enzymes, cofactors and major metabolic pathways (Krebs cycle, methylation, steroidogenesis, catecholamine synthesis), applied to functional clinical practice.
Applied Cell Biology & Signaling
A course covering the cell membrane, receptors, gene expression, epigenetics and cytokines, with a strong focus on their clinical implications.
Homeostasis & Biochemical Systems Integration
A course focused on glycemic homeostasis (insulin/glucagon, AMPK, glucose peaks/hypoglycemia), energy homeostasis (thyroid, cortisol, mitochondria), hormonal homeostasis (hypothalamic–pituitary–thyroid/adrenal/gonadal axes), and biological rhythms, in order to connect biochemistry with major clinical regulatory systems.
Immunology & Chronic Inflammation
Immune Foundations & Low-Grade Inflammation
A course dedicated to the fundamentals of innate and adaptive immunity, key cytokines, and a clear clinical understanding of low-grade inflammation.
Systemic Inflammation & Autoimmunity
A course focused on systemic inflammation biomarkers, the gut microbiota–intestinal permeability–endotoxemia axis, and the fundamental mechanisms of autoimmunity (Hashimoto’s thyroiditis, lupus, rheumatoid arthritis).
Inflammatory Assessment, Clinical Cases & Anti-Inflammatory Levers
A course centered on integrated interpretation of inflammatory lab panels, clinical case analysis (fatigue, functional pain, Hashimoto’s, digestive disorders), and the main nutritional and lifestyle levers to modulate inflammation.
Differential Gastroenterology
Digestive Physiology & Maldigestion
A course focused on gastrointestinal physiology and the mechanisms of non-infectious maldigestion and malabsorption, along with their clinical and biological manifestations.
Gut Microbiota & Mucosal Permeability
A course dedicated to the fundamentals of the gut microbiota, mucosal permeability (intestinal and oral), and their impact on systemic inflammation.
Digestive Inflammation & Gut–Brain Axis
A course centered on low-grade digestive inflammation, gut–brain interactions, and the clinical integration of non-infectious functional IBS.
Differential Digestive Assessment & Clinical Integration
A course dedicated to the interpretation of standard digestive lab panels, functional analysis (inflammation, permeability, enzymes), and the construction of a differential clinical evaluation strategy.
Metabolism & Mitochondria
Mitochondrial Physiology & Energy Metabolism
A course focused on ATP production, energy pathways (glucose, lipids, amino acids), and the role of thyroid hormones, cortisol, insulin, and the gut microbiota in bioenergetics.
Circadian Rhythms, Sleep & Energy Regulation
A course dedicated to the impact of the sleep–wake cycle, cortisol, body temperature, melatonin, and dopamine on daily energy regulation.
Functional Fatigue & Energy Neurotransmitters
A course centered on the different types of functional fatigue and the role of neurotransmitters (dopamine, noradrenaline, serotonin, melatonin) in physical and mental energy.
Functional Metabolic Assessment & Clinical Integration
A course dedicated to the interpretation of basic metabolic panels (HbA1c, insulin, ferritin, cortisol, FT3, hs-CRP) and their integration into the analysis of functional fatigue patterns.
Systemic Integration & Advanced Practice
Preventive Biomarkers & Systemic Health
Identification and interpretation of key preventive biomarkers (inflammatory, metabolic, cardiovascular, hormonal, immune, micronutritional, renal, hepatic, urinary and circadian) to build clinically relevant screening and longevity panels.
Differential Lab Interpretation (Systemic Approach)
Integrated interpretation of lab results (thyroid, metabolism, inflammation, adrenal function, liver, digestion, micronutrient status) to identify multisystem functional patterns and master essential standard lab readings.
Functional Nutrition (Low-Carb, Anti-Inflammatory & Targeted Approaches)
Dedicated to main dietary models (Mediterranean, low-carb/keto, vegetarian, elimination), balanced plates, and targeted functional plates (microbiota support, detoxification, metabolic support, anti-inflammatory nutrition).
Hepatic & Environmental Detoxification
Functional liver physiology, detoxification pathways (Phase I, II & III), metabolic and environmental toxic load, support strategies, and functional interpretation of liver panels.
Adaptive Physical Activity
Physical activity as a biological signal (metabolic, hormonal, mitochondrial, immune), understanding exercise modalities, and prescribing the optimal 'sweet spot' based on fatigue, stress, and sleep.